What we love about Tesamorelin:
Tesamorelin (Tesa for short) is possibly the “best” growth hormone peptide and is also FDA-approved for specific conditions. However, it is expensive. We usually only suggest it to be used in the morning for hard-core athletes who on tough training days need some extra recovery support while using CJC1295/Ipamorelin at night.
Overview:
Discover the benefits of Tesamorelin, an FDA-approved injectable peptide that stimulates growth hormone production. Learn how it can help restore growth hormone levels, improve cognitive function, maintain muscle mass, and reduce visceral fat. Find out more about the potential side effects and safety considerations.
Tesamorelin is a GHRH analog that has been shown to increase growth hormone and IGF-1 levels. This injectable peptide promotes the generation of HGH (Human Growth Hormone) in a way that mimics the natural process. It binds to and activates human GHRH receptors with the same efficacy as the body’s own GHRH. Notably, there is no considerable data demonstrating a major effect on other pituitary hormones in the body.
What’s Tesamorelin?
Tesamorelin also known as Egrifta, is an FDA-approved injectable peptide functioning as an analog of growth hormone-releasing hormone (GHRH). In simpler terms, it is a synthetic version of GHRH. When administered, Tesamorelin prompts a chain reaction leading to increased production of growth hormone, potentially contributing to extended lifespan and the restoration of youthful health.
The pituitary gland produces human growth hormone, which plays a vital role in various physiological processes such as normal childhood development, regulation of body composition, muscle and bone growth, metabolism of sugar and fat, and heart function. As natural growth hormone levels decline with age, a synthetic peptide like Tesamorelin that boosts growth hormone production may counteract the age-related deterioration of the body. Consequently, Tesamorelin is anticipated to have a positive impact on anti-aging and longevity
How Does Tesamorelin Work?
Tesamorelin targets the pituitary gland at the base of the brain. This gland regulates hormones. Tesamorelin interacts with GHRH receptors on the pituitary gland, causing it to release growth hormone. Growth hormone has a wide range of effects on the body, but it is particularly important for fat metabolism. Tesamorelin’s major effect is to reduce visceral fat, which is found deep inside the abdominal region and has been linked to an increased risk of metabolic and cardiovascular diseases.
Effects of Tesamorelin
Restoring GH
As individuals age, there is a gradual decline in growth hormone, contributing to several age-related health issues, alongside the decline in various other hormones. This set of conditions associated with aging includes an increase in body fat, a decrease in lean muscle mass, and a decline in cognitive function. by stimulating the pituitary gland and promoting the release of growth hormone-releasing hormone (GHRH), Tesamorelin can restore restoring growth hormone levels to a more normal range.
Improving Cognitive Function
According to research, Tesamorelin has shown significant promise for improving problem-solving abilities, attention upkeep, planning abilities, and word memorization in both healthy older persons and those with mild cognitive impairment. Tesamorelin, by restoring normal growth hormone levels, may help to restore synaptic plasticity and hence increase mental capacity. It is vital to highlight that longer treatment periods are required to fully evaluate tesamorelin’s possible impact on brain health during natural aging.
Maintaining Muscle Mass
A study found that providing growth hormone medications to those with deficits could efficiently restore muscle strength, with the positive effects being more obvious in younger people. As a result, by acting as a growth hormone-releasing hormone (GHRH) analog, Tesamorelin can increase and regulate the amount of lean muscle mass in both young people with growth hormone deficiency and healthy adults.
Minimizing Visceral Fat
Tesamorelin has been shown to improve visceral fat burning by increasing growth hormone levels. Fat oxidation is the breakdown of stored fat into fatty acids, which are then transformed into energy for a variety of biological processes. Tesamorelin, in plain terms, aids in the burning of fat surrounding the abdominal organs, which is then used as an energy source. Importantly, Tesamorelin has no effect on fat tissue under the skin.
Benefits of Tesamorelin
Tesamorelin Offers Several Benefits, Including:
- Increased production of HGH (human growth hormone)
- Elevated levels of IGF-1 (Insulin Growth Factor-1) without necessitating adjustments to glucose parameters
- Lowered triglycerides
- Diminished Visceral Adipose Tissue (VAT)
- Reduced Carotid Intima-Media Size (cIMT)
- Enhanced cognition in adults aged 60 and above.
Drawbacks
Here are potential side effects associated with Tesamorelin. It’s important to immediately inform your healthcare providers if you encounter any of the following:
- Allergic reaction
- Depression
- Nausea
- Vomiting
- Pain
- Redness or irritation at the injection site
- Tingling or numbness in hands and feet
- Swelling of ankles, feet, or hands
Is Tesamorelin Safe?
Tesamorelin is generally considered safe as it naturally stimulates growth hormone production. The administration of Tesamorelin can lead to a slight increase in glucose levels, resulting in minimal changes in insulin sensitivity. It’s important to note that Tesamorelin does not cause insulin resistance, and prolonged use can reverse glucose levels to normal.
While Tesamorelin is not FDA-approved for anti-aging or longevity purposes, it has received FDA approval for reducing visceral fat in individuals with an immune system deficiency condition. It’s crucial to understand that Tesamorelin is not intended for weight loss and may not have an overall impact on body weight. In summary, Tesamorelin shows promise in addressing various age-related conditions for promoting longevity. However, further research is needed before this peptide becomes widely available.
Conclusion
Tesamorelin is an FDA-approved injectable peptide, that mimics the natural process of growth hormone release by targeting the pituitary gland. It effectively increases growth hormone and insulin-like growth factor levels, contributing to potential benefits in anti-aging and health restoration. Tesamorelin has demonstrated positive effects such as restoring growth hormone levels, improving cognitive function, maintaining muscle mass, and reducing visceral fat. These benefits make it a promising option for addressing age-related health issues.
FAQ
Does Tesamorelin Cause Water Retention?
It’s possible to experience swelling (fluid retention in some parts of your body when using Tesamorelin.
Does Tesamorelin Cause Weight Loss?
No, Tesamorelin is not used to help with losing weight.
How Often Do You Inject Tesamorelin?
Tesamorelin is usually injected once daily. The best practice is to use it at the same time each day.
Can You Eat After Taking Tesamorelin?
You should wait for about an hour before having a meal after taking Tesamorelin.
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