What we love about BPC-157:

What’s not to love? BPC-157 is most well-known for helping with ligaments, tendons, and muscle injuries. Even still, the best benefit is lowering systemic full-body inflammation. On top of that, BPC-157 is known to heal the gut! This is a top 5 peptide.

Overview:

What we love about BPC-157:

BPC-157 offers numerous benefits across various areas, such as effectively addressing acute and chronic inflammation, promoting ligament and tendon healing, and notably aiding in the healing of the gut. While it is widely recognized for its healing properties, it is important to note that BPC-157 is much more than just an injury healer. Discover more about its incredible capabilities below!

BPC-157 is a synthetic peptide that’s being studied for possible regenerative abilities. While it demonstrates significant effectiveness in promoting recovery for rats undergoing toxic or surgical trauma, there is currently limited evidence supporting its benefits for humans. Despite this, the BPC 157 peptide became popular as a therapy for a variety of diseases. This naturally occurring peptide contains 15 amino acids generated from human gastric secretions it’s also known as Body Protecting Compound 157.

For therapy, BPC-157 is used in concentrated form which is accessible in injectable, topical, and oral supplement variants. The decision between these distribution techniques is determined by the individual ailment that is being addressed. Despite this, keep in mind that therapy should only be administered under the direct supervision of a medical practitioner.

How Does BPC-157 Work?

BPC-157 operates through various potential mechanisms of action, which might overlap. These include promoting the synthesis of nitric oxide, activating cells involved in tissue repair, stimulating the synthesis of growth factors, and inhibiting inflammation. BPC-157 is generally considered safe for use as it is naturally found in gastric juices and is well tolerated by the body.

BPC-157 can be administered orally, topically, or through injection. Ordinarily, oral ingestion of peptides like BPC-157 wouldn’t be expected to directly impact tissues beyond the gastrointestinal tract, such as tendons and nerves, as peptides are not easily absorbed into circulation. However, rat studies indicate that oral consumption can have systemic effects, implying that the potential of this delivery mechanism should not be ignored.

Benefits of BPC-157

BPC-157 peptide therapy offers a range of benefits, including:

• Promoting Wound Healing
• Accelerating Tissue Regeneration
• Reducing Inflammation
• Increasing Blood Flow
• Relieving Joint Pain
• Boosting Immune Function
• Improving Muscle Strength and Endurance

When integrated into a comprehensive care plan and coupled with healthy nutrition, BPC-157 appears to have remarkable effects. Ongoing research aims to explore additional benefits that BPC-157 therapy may provide.

Disadvantages of BPC-157

BPC-157 therapy is associated with some known side effects, although not everyone experiences them. It’s important to note that with any supplement or medication, there is a possibility of side effects. Specifically, BPC-157 may lead to:

• Nausea
• Diarrhea
• Dizziness

However, ensuring the correct dose under the supervision of a medical provider can help mitigate the risk of experiencing these side effects.

Is BPC-157 Legal?

In a nutshell, BPC-157 isn’t approved for human consumption, despite some websites suggesting it is available with a prescription. The World Anti-Doping Agency (WADA) has added BPC-157 to its list of banned substances. This implies that athletes who use it may be disqualified if they test positive for drugs. Although some internet merchants mark it as for research purposes exclusively, it is widely assumed that it is being sold for human consumption.

The FDA has started taking action against compounding pharmacies that produce BPC-157, particularly those that use bulk research-grade chemicals. In February 2020, the FDA issued an advisory noting that compounds such as BPC-157 must be fully approved before compounding pharmacies can legally manufacture them for human use. Future measures by the FDA and the Federal Trade Commission (FTC) may result in crackdowns on compounding pharmacies and internet vendors. While these regulatory initiatives may influence sales, the history of the stem cell sector implies that BPC-157’s availability may not be fully prohibited. According to FDA, BPC-157 is banned due to the increased risk of immunogenicity, peptide-related impurities, and limited safety-related information.

BPC-157 Research Facts

A comprehensive review paper examining the role of BPC-157 in aiding musculoskeletal soft tissue healing found that it promotes tissue repair, reduces inflammation, and enhances the healing of various tissues, including muscles, tendons, and ligaments.

In a separate study, BPC-157 demonstrated its potential to facilitate tendon healing by increasing the responsiveness of tendon fibroblasts to growth hormones. Additionally, the peptide was observed to boost collagen production by tendon fibroblasts, suggesting its potential as a therapeutic agent for promoting tendon healing.

Another review highlighted several neurological benefits of BPC-157, including:

1. Improving cognitive function: Studies indicate that BPC-157 can enhance cognitive function, improving memory and learning performance in rats.
2. Promoting neurogenesis: BPC-157 has been found to stimulate the growth of new neurons in the hippocampus, a brain region crucial for learning and memory.
3. Protecting neurons from damage: BPC-157 has shown the ability to shield neurons from damage caused by various factors like ischemia (stroke), hypoxia (lack of oxygen), and excitotoxicity (excessive activation of glutamate receptors).
4. Reducing inflammation: BPC-157 exhibits anti-inflammatory properties, which could be beneficial for various central nervous system disorders, such as Alzheimer’s disease, Parkinson’s disease, and multiple sclerosis.

While BPC-157 has been extensively studied in preclinical animal models, the results thus far have been highly promising.

What’s the Recommended Dosage?

While BPC-157 hasn’t been thoroughly studied on humans, the recommended dose is based on rat studies, where the peptide was delivered orally. The oral dose that was effective in rats, 10 μg/kg, is estimated to be equivalent to 1.6 μg/kg, or:

• 125 mcg for a 170lb person
• 145 mcg for a 200lb person
• 165 mcg for a 230lb person

However, the most common approach is simply 250-333mcg SubQ injection morning and night, until benefits are reached, while taking weekends off. SubQ is by far more beneficial than oral. The only benefit of oral is strictly gut repair, and will not provide the healing injury and recoverty properties.

Conclusion

BPC-157, also known as Body Protecting Compound 157, is under scrutiny for its potential regenerative abilities. While research has shown positive effects in promoting recovery for rats, evidence supporting its benefits in humans is limited. BPC-157 operates through various mechanisms, including promoting nitric oxide synthesis, tissue repair, growth factor synthesis, and anti-inflammatory effects. BPC-157 therapy offers benefits like wound healing, tissue regeneration, reduced inflammation, increased blood flow, joint pain relief, immune function boost, and improved muscle strength. However, it is crucial to note that BPC-157 is not approved for human consumption, and its availability may face regulatory challenges.

FAQ

Does BPC 157 Have the Ability to Increase Testosterone Levels?

There’s not enough strong evidence to say that BPC-157 can boost testosterone, either directly or indirectly. While some things can affect hormone levels, we don’t know of a clear way that BPC-157 increases testosterone.

Does BPC 157 Have Any Impact On the Heart?

According to research, when it comes to heart problems, using stable gastric pentadecapeptide BPC-157 in therapy can help treat issues like heart attacks, heart failure, pulmonary hypertension, and arrhythmias, and even prevent or reverse blood clot formation.

Does BPC 157 Promote Muscle Growth?

While this peptide can shorten the recovery time and reduce inflammation, it does not have anabolic effects.

Does BPC-157 Burn Fat?

Yes. Given that BPC-157 supports digestive health, it may also play a role in regulating weight and promoting fat burning.

What Are Other Names for BPC-157?

The BPC-157 peptide is also known as PL 14736, PL-10 and Bepecin.