What we love about Thymosin Alpha 1:
Thymosin Alpha 1 should be on hand in every household, and even taken while traveling. In the event of a viral infection (cold, flu, COVID, etc.) there is in our opinion no better solution. This peptide is one of the 5 most important peptides that everybody should know about. Thymosin Alpha 1 is approved for the treatment of COVID-19 in over 30 countries. However, it has never been approved for this treatment by the FDA in the United States.
Thymosin alpha 1 (Tα1) is a naturally occurring peptide found in the thymus that can regulate, increase, and restore immunological function. It has been used to treat impaired immune systems as well as malignancies. Furthermore, it acts as a booster for vaccination responses and has been used to lessen the severity and mortality associated with sepsis and numerous infections.
Thymosin alpha 1 is commonly administered for chronic viral diseases, primarily to boost immunity. It also plays a role in managing inflammation linked to chronic diseases, potentially alleviating symptoms like excessive fatigue.
What’s Thymosin Alpha 1?
Thymosin alpha 1, a thymic endogenous peptide, has 28 amino acids and is naturally produced by the thymus. It is N-terminally acetylated and produced by the proteolytic processing of prothymosin, a precursor, by legumain, a lysosomal endopeptidase in mammals. Both legumain and thymosin alpha 1 are distributed across various tissues, with elevated levels found in lymphoid tissue.
T cells, crucial for immunity, mature in the thymus and are released through signals from thymosin alpha 1. This prompts immune cells to locate and eliminate harmful foreign agents in the body. Thymosin alpha 1 has shown the ability to enhance specific T and dendritic cells, essential defenses for individuals with compromised immunity or infections.
Thymosin alpha 1 exhibits pleiotropic characteristics, producing multiple effects. It can bolster innate immunity during periods of need and regulate immunity when excessive. This thymic peptide possesses the capability to restore balance in the immune system across diverse pathological and physiological conditions.
Is Thymosin Alpha 1 FDA-Approved?
Thymosin alpha 1 is FDA-approved and marketed globally as “Zadaxin.” It’s approved for treating malignant melanoma, Hepatitis B and C, and influenza. It is also employed to bolster immune systems weakened by chemotherapy. Ongoing studies are exploring its antiviral properties, potential as a cancer treatment, and its use as a potent antioxidant. Additionally, it is being investigated as a supplementary treatment for tick-borne infections and for immune modulation and enhancement.
Zadaxin™ has been approved in 30 countries worldwide to address hepatitis and cancer. In clinical trials, it has been utilized to support immunity, either as a standalone treatment or in combination with existing allopathic medications. Currently, Zadaxin™ is undergoing Phase III trials for treating hepatitis C and Phase II trials for hepatitis B in the United States.
Thymosin Alpha 1 Mechanism of Action
Thymosin alpha 1 has been shown in laboratory studies to increase the differentiation and maturation of T-cells, including CD4+, CD8+, and CD3+ cells. When mitogens or antigens activate thymosin alpha 1, it increases the synthesis of immune-related chemicals as well as the expression of the IL-2 receptor. It increases natural killer (NK) cell activity, MIF synthesis, and antibody reactivity to T-cell-dependent antigens.
Thymosin alpha 1 treatment in vivo to animals with immunosuppression caused by chemotherapy, tumors, or irradiation has been found to protect against cytotoxic bone marrow damage, tumor growth, and opportunistic infections. This leads to longer survival times and a larger number of survivors.
Benefits of Thymosin Alpha 1
There are numerous benefits of Thymosin alpha 1 as it can:
- Help the immune system.
- Support the body’s defense against infections.
- Aids in reducing cell death.
- Eases symptoms of both short-term and long-term infections.
- Fights against infections and some types of cancer.
- Acts against bacteria, viruses, and fungi.
- Provides protection against tumors.
- Boosts the effectiveness of vaccines.
- Limits the spread of viruses.
- Protects against damage from harmful substances.
Side Effects and Risks of Thymosin Alpha 1
Thymosin alpha 1’s suggested subcutaneous dosages have been proven to be both safe and effective. This peptide has been used for over 40 years, with patients reporting good tolerance and a very low toxicity profile. Thymosin alpha 1 has been shown to be well tolerated even in patients with kidney disease undergoing hemodialysis and liver disease.
In rare cases, reported adverse responses include:
- Redness of the skin
- Joint pain
- Skin rash
Thymosin Alpha 1 is not advisable for individuals with hypersensitivity reactions, as it may cause allergic responses. Allergic symptoms may include itching, difficulty breathing, swelling of the face or throat, and a rapid heartbeat. If any of these symptoms occur, it is essential to consult your doctor immediately.
This peptide is not recommended for those who are at high risk of infection, such as those with a compromised immune system or who have recently had surgery or invasive procedures. In these circumstances, thymosin alpha 1 must be used with caution to avoid infection. Furthermore, the medicine should not be administered to immunocompromised individuals or those with weakened immunity, such as organ transplant recipients, as it may increase the risk of infection.
Thymosin Alpha 1 Dosage
Usually, Thymosin alpha 1 is administered via subcutaneous injections. It’s used twice a week with the normal single dosage varying from 0.8 to 6.4 mg, with multiple doses ranging from 1.6 to 16 mg over five to seven days. Thymosin alpha 1 is used to treat a variety of ailments, including liver disease, cancer, and autoimmune disorders. Depending on the condition the dosage may be adjusted. It has been shown to be well-tolerated and safe in various applications. However, it’s important to consult a peptide medical professional before implementing any medicine into your regime.
Conclusion
Thymosin Alpha 1 (Tα1) is a natural peptide produced in the thymus, renowned for its ability to boost and regulate the immune system. Used for over 40 years, it’s FDA-approved as “Zadaxin” and is globally recognized for treating conditions like hepatitis, cancer, and influenza.
Tα1 acts as a superhero for our immune cells, enhancing T-cell maturation, increasing natural killer cell activity, and improving antibody reactivity. It aids in reducing cell death, fights infections and certain cancers, boosts vaccine effectiveness, and limits virus spread. Its benefits span from supporting the immune system to protecting against tumors and harmful substances.
FAQ
What Happens If You Have Too Much Thymosin?
Having too much thymosin might result in an increased production of T cells, leading to a higher-than-normal number of lymphocytes, a condition known as lymphocytosis.
Why is Thymosin Called a Youth Hormone?
Thymosin is known as the “youth hormone” because it plays a key role in T cell development in the thymus and is most active during youth. Thymus activity declines with age, and the phrase refers to its link with youthful immune system function.
Where Do You Inject Thymosin Alpha 1?
Thymosin Alpha 1 is administered using an insulin needle through a subcutaneous injection, which means it is injected just below the skin. After injecting thymosin, it should be stored in the refrigerator.
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